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Sunday, 25 November 2007

Genetic engineering (1)

Introduction
Basic genetics to genetic engineering
1866 Mendel - Principle of Inheritance
1900 de Vries, Correns, van Tschermak - rediscover Mendel's rule
1905 Bateson - word "Genetics"
1901 Johannsen - word "Genes"
1928 Avery, Macleod, McCarthy- DNA is genetic material
1953 Watson, Crick - double helix DNA
Beginning of genetic engineering techniques
1970 Nathans, Smith - restriction enzymes
1970 reverse transcriptase
1976 antibody diversities
1977 split genes: introns and exons
1977 Sequencing techniques
1982 Supermice: Growth Hormone Gene Transfer
1983 Ribozymes
1985 Polymerase chain reaction (PCR), DNA fingerprint
1990 CFTR gene for cystic fibrosis
1993 IT15 gene for Huntington disease
1997 Telomerase gene
2003 First draft of Human Genome

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